«San Pedro it’s the safest substance I’ve ever come across. It’s safer than coffee, it’s safer than anything that I know»

Marc Lane defines himself as a ‘phoenician world traveler’ and has been living in Ibiza for the last 15 years. It’s not unusual seeing him around, giving to the people some microdoses of a dark and sweet jam made of San Pedro that Marc himself cooks at home: «I’ve spent years trying to find a nice flavour to wachuma, because people usually feels its flavour beeing too bitter».

The effect of San Pedro (Echinopsis pachanoi) in microdose are subtle but crystal clear. It’s like the doors of perception suddently were clystal clear, using the famous words of Aldous Huxley. The british novelist had a revealing experience with mescaline, the active principle of San Pedro, when he wrote ‘The doors of perception’ and ‘Heaven and Hell’, two brief essays that pioneered the psychedelic literature.

«The man who comes back through the Door in the Wall will never be quite the same as the man who went out. He will be wiser but less sure, happier but less self-satisfied, humbler in acknowledging his ignorance yet better equipped to understand the relationship of words to things, of systematic reasoning to the unfathomable mystery which it tries, forever vainly, to comprehend».

«This medicinal plant that is called San Pedro, ‘Wachuma‘ or ‘Iwakoya‘, but a lot of people like to refer to the active ingredient which is mescaline», explains Marc while pointing one of the dozens cacti that grows in his garden. His relantionship with the plant started 12 years ago, when «some gentleman was here [in Ibiza] and he had a bag of San Pedro powder that he brought from South Africa. When I started taking it, it made me feel really really good…. I wasn’t taking full doses, but just enough to… it was like turning on the light to reality», explains Marc Lane.

«For a few years, I got involved a little bit with with ayahuasca and other different experiences, but the San Pedro was always there there in the background somewhere», recalls Marc. The epiphany was about to happen:

«Five years ago, I finally went to Peru and I made my direct connection with the plant. I could not find anybody to really teach me about the ‘Wachuma’, but instead I was learning from directly from the plant itself. It was guiding me, so when I was coming back I wanted to bring some with me and one of my maestros told me let’s go ask for the ‘apus’ -the great mountain spirits- for permission. I could have just gone to the market and bought it, but instead we went up to mountain and we made an offering to the ‘apus’. At that moment, I received a message and the message was ‘You take this and you give it to everybody. You just put it in your mouth; no ceremonies, no stories, no complications. You don’t put yourself between the plant and the people. The cactus is a lot smarter than you or anybody else».

Why do you think the ‘wachuma’ has chosen you for this ‘mission’. «Well, the cactus is very very powerful but it doesn’t have hands neither legs, it doesn’t feed doesn’t have a mouth, so i’m just letting him use mine», repplies Lane.

Since then and following this aim for spreading the plant, Marc has been growing the cacti and developing different ways of taking the San Pedro. «The most important thing trying to make it taste good, so be more pleasant to take because some people say that it tastes bad».

Applications for San Pedro

Mescaline its well kwown for its psychoactive effects (due to mescaline, the same active principle of peyote). Nevertheless, this is not the effect Marc it’s looking for with the microdoses: «To me it’s like taking it like you would take a normal medicine, taking a little pill every day in small quantities. I don’t go for large doses or for psychedelic experiences. I think a slow buildup is a much more effective long-term therapeutic, and it’s also a lot easier because it’s a much easier to manage».

Taste is relevant, but safety it’s much more important for Marc. There is no much information about safety with mescaline, but Marc Lane defends its ‘observational experience’: «I have given San Pedro to literally thousands of people ranging from very small children to very old people. There has never been a bad side effect. It’s the safest substance I’ve ever come across. It’s safer than coffee, it’s safer than anything that I know. Before that, it works for many different conditions. for a person that is let’s say okay, it improves your mood but it also improves sleeping for insomnia and also for children with ADHD [Attention Deficit Hypeactivity Disorder] or even autism.

There are some parents that have been giving very small doses of San Pedro to children with autism or children with ADHC, and the results have been incredible: the anxiety is gone, the stress is gone all this tendency to to flip out just gets smoothed; all is serenity and peace (…) Nothing gives me the satisfaction that when one of these children just comes up to me and hugs me… I just start crying».

The ‘antidepressant cacti’?

There is a vigorous movement in the U.S. trying to ‘decriminalize nature’, more specifically, all the psychoactive plants and fungi used for millenia by humankind. In this aspect, Marc considers that «San Pedro should be legalized and it should even be classified potentially as a nutritional supplement». Nevertheless, Echinopsis pachanoi «can basically replace most psychiatric medication. It is more effective than antidepressants and than most anti-anxiety medicines and also than most mood elevators out there, without any side effects and that’s also one of the reasons I believe that it’s always been kept on the side: because it basically take out a big chunk of pharmaceutical business». While other psychedelic compounds like MDMA or LSD also work in different ways, they also have their side effects some of them are addictive and, eventually, are very dangerous to stop taking, this one is is anti-addictive actually: the more you take the less you want to take».

I ask Marc if there are any scientific studies to support his findings in the issues of those patologies: autism, depression and ADHD: «It depends on what you consider a scientific study. There is no scientific studies for San Pedro or mescaline in general, and the ones that there are very small. I mean, if we want to look for example even the work that MAPS is doing with MDMA, even all their trials have been with a few dozen people. Is that a real study ? I’ve been doing a real life study with thousands of people for years, perhaps not scientific but surely observational, and I found out that ‘wachuma’ is both safe, useful and powerful».


‘The doors of perception’, Aldous Huxley (1954)

«Las plantas maestras pueden paliar la crisis de salud mental de los olvidados por el sistema de salud de EE.UU.», Plantaforma, 18 de marzo de 2022

-‘Decriminalize Nature, the citizen’s movement behing de decrimalisation of psychdelics in the U.S.‘, BMed, 22 de marzo de 2022

One thought on “«San Pedro it’s the safest substance I’ve ever come across. It’s safer than coffee, it’s safer than anything that I know»

  • 01/09/2022 at 19:39

    Excellent job

    The evidence is clearly in the word of the people is where the evidence of safeness is

    Personally believe this is the case with “plant medicines” in general.

    New psychedelic research in general telling us same things we were told were so dangerous had zero medical use.

    COVID and the 60s taught us no longer to believe statistics or government propaganda.

    Social media I guess helps at and individual level to know more by hearing from Individuals like Marcs accounts a “man with nothing to gain by telling lies” (gives it away? 🧐)

    I hope to hear more about this topic here..and plant medicine stories here.

    Great job, well done.

    James McNee


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